BDBM50333734 7-chloro-N,N-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)-5-(trifluoromethyl)benzo[b]thiophene-2-carboxamide::CHEMBL1644013

SMILES CN(C)C(=O)c1sc2c(Cl)cc(cc2c1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1)C(F)(F)F

InChI Key InChIKey=MLWXAWHTWHMUAG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333734   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333734(7-chloro-N,N-dimethyl-3-(4-(2-(3-tosylureido)ethyl...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333734(7-chloro-N,N-dimethyl-3-(4-(2-(3-tosylureido)ethyl...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333734(7-chloro-N,N-dimethyl-3-(4-(2-(3-tosylureido)ethyl...)
Affinity DataKi:  16nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed