BDBM50333729 5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)benzo[b]thiophene-2-carboxamide::CHEMBL1644008

SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(N)=O

InChI Key InChIKey=LAYMRPNOHFPLQJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333729   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333729(5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333729(5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...)
Affinity DataKi:  171nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333729(5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...)
Affinity DataKi:  650nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed