BDBM50333652 CHEMBL1643121::N-(4-iodophenyl)-4-oxo-4H-chromene-3-carboxamide

SMILES Ic1ccc(NC(=O)c2coc3ccccc3c2=O)cc1

InChI Key InChIKey=YBVRKIFSPHOAAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333652   

TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333652(N-(4-iodophenyl)-4-oxo-4H-chromene-3-carboxamide |...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus-infected BTI insect cells after 15 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333652(N-(4-iodophenyl)-4-oxo-4H-chromene-3-carboxamide |...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50333652(N-(4-iodophenyl)-4-oxo-4H-chromene-3-carboxamide |...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed