BDBM50333560 2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-3,N-dimethyl-benzamide::CHEMBL1642134

SMILES CNC(=O)c1cccc(C)c1Nc1nc(Nc2ccc3CCN(CCOC)CCc3c2)ncc1Cl

InChI Key InChIKey=HWQSQWILDDXRQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333560   

TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333560(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50: 26nMAssay Description:Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333560(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of c-Met expressed in human GTL-16 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333560(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of insulin receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed