BDBM50333542 5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfonyl)-2,3-dihydro-1H-quinolin-4-one::CHEMBL1642117

SMILES CN1CCN(CC1)c1cccc2N(CCC(=O)c12)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=TZMHJAWORUSIEG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50333542   

Target5-hydroxytryptamine receptor 6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 333nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 760nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 438nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 620nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 2.92E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333542(5-(N-methyl-piperazin-1-yl)-1-(naphthalene-2-sulfo...)
Affinity DataIC50: 1.79E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed