BDBM50333541 7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfonyl)-2,3-dihydroquinolin-4(1H)-one::CHEMBL1642116

SMILES CN1CCN(CC1)c1ccc2C(=O)CCN(c2c1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=YLSBAGZHIBFNRL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50333541   

Target5-hydroxytryptamine receptor 6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 672nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 366nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 5.19E+3nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 143nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 3.61E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50333541(7-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 188nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HeLa cells assessed as inhibition of 5-HT-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed