BDBM50333455 (2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine-3,4-diol::CHEMBL1641739

SMILES CCCC[C@@H]1N[C@@H](CO)[C@H](O)[C@H]1O

InChI Key InChIKey=ZBUKLPRLOKVWJG-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50333455   

TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Wistar rat small intestine isomaltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of rat intestinal isomaltase using isomaltase as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataKi:  85nMAssay Description:Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed