BDBM50333281 CHEMBL1645111::N1-(4-chloro-3-fluorophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide

SMILES CC1(C)CC(CC(C)(C)N1)NC(=O)C(=O)Nc1ccc(Cl)c(F)c1

InChI Key InChIKey=WNIRIUAQGASKHI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333281   

TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333281(N1-(4-chloro-3-fluorophenyl)-N2-(2,2,6,6-tetrameth...)
Affinity DataIC50: 7.48E+4nMAssay Description:Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333281(N1-(4-chloro-3-fluorophenyl)-N2-(2,2,6,6-tetrameth...)
Affinity DataKd:  760nMAssay Description:Binding affinity to HIV1 YU2 gp120 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed