BDBM50333236 CHEMBL1645262::N1-(4-chloro-3-fluorophenyl)-N2-((1-cyclopropylpyrrolidin-3-yl)methyl)oxalamide

SMILES Fc1cc(NC(=O)C(=O)NCC2CCN(C2)C2CC2)ccc1Cl

InChI Key InChIKey=WJMIBQNZONFNCE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333236   

TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333236(N1-(4-chloro-3-fluorophenyl)-N2-((1-cyclopropylpyr...)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333236(N1-(4-chloro-3-fluorophenyl)-N2-((1-cyclopropylpyr...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to HIV1 YU2 gp120 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed