BDBM50333233 CHEMBL1645265::N1-(4-chloro-3-fluorophenyl)-N2-(5-azaspiro[3.5]nonan-8-yl)oxalamide

SMILES Fc1cc(NC(=O)C(=O)NC2CCNC3(CCC3)C2)ccc1Cl

InChI Key InChIKey=JSEOESVFYKWYEF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333233   

TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333233(N1-(4-chloro-3-fluorophenyl)-N2-(5-azaspiro[3.5]no...)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(HIV-1)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50333233(N1-(4-chloro-3-fluorophenyl)-N2-(5-azaspiro[3.5]no...)
Affinity DataKd:  600nMAssay Description:Binding affinity to HIV1 YU2 gp120 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed