BDBM50333177 1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-L-prolinamide dihydrochloride::CHEMBL1644850

SMILES CC(C)Cc1nc(C)c(CC(=O)N2CCC[C@H]2C(N)=O)c(-c2ccc(C)cc2)c1CN

InChI Key InChIKey=ILRWGNNTDUTQFY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333177   

TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50333177(1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DDP4 in human Caco2 cells after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50333177(1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat kidney DDP2 after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50333177(1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DDP8 expressed in HEK293-F cells after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50333177(1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DDP9 expressed in HEK293-F cells after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed