BDBM50333110 CHEMBL1631113::N-(1-(indolin-1-yl)-3-methyl-1-oxopentan-2-yl)benzamide

SMILES CCC(C)C(NC(=O)c1ccccc1)C(=O)N1CCc2ccccc12

InChI Key InChIKey=ZVJMRPCDQIPYRL-UHFFFAOYSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333110   

TargetMajor prion protein(Mouse)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50333110(N-(1-(indolin-1-yl)-3-methyl-1-oxopentan-2-yl)benz...)
Affinity DataKd:  5.12E+4nMAssay Description:Binding affinity to mouse recombinant PrP (121-231) after 10 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMajor prion protein(Golden hamster)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50333110(N-(1-(indolin-1-yl)-3-methyl-1-oxopentan-2-yl)benz...)
Affinity DataEC50:  7.43E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMajor prion protein(Golden hamster)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50333110(N-(1-(indolin-1-yl)-3-methyl-1-oxopentan-2-yl)benz...)
Affinity DataKd:  5.12E+4nMAssay Description:Binding affinity to Syrian hamster PrPCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed