BDBM50333094 (R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo[15.3.1.04,9]henicosa-1(21),4(9),5,7,17,19-hexaen-12-yl)hexanoic acid hydroxyamide::CHEMBL1631918

SMILES COc1cc2CCCO[C@H](CCCCCC(=O)NO)C(=O)Nc3ccccc3OCc(c2)c1

InChI Key InChIKey=HIEFOIISQBSAEQ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50333094   

TargetHistone deacetylase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 102nMAssay Description:Inhibition of human HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 425nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 454nMAssay Description:Inhibition of human HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 271nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 322nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333094((R)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 174nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed