BDBM50333088 (S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo[15.3.1.04,9] henicosa-1(21),4(9),5,7,15,17,19-heptaen-12-yl)hexanoic acid hydroxyamide::CHEMBL1631914

SMILES COc1cc2COc3ccccc3NC(=O)[C@H](CCCCCC(=O)NO)OC\C=C/c(c2)c1

InChI Key InChIKey=LMOIMHSPFQECJG-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50333088   

TargetHistone deacetylase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 198nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed