BDBM50333085 (R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,14-dioxa-5-azabenzocyclododecen-7-yl)hexanoic acid hydroxyamide::CHEMBL1631911

SMILES ONC(=O)CCCCCC1OCCCCCCOc2ccccc2NC1=O

InChI Key InChIKey=WCTLKUHJSQSAOJ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50333085   

TargetHistone deacetylase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 878nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 738nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 687nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 683nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333085((R/S)-6-(6-Oxo-6,7,10,11,12,13-hexahydro-5H,9H-8,1...)
Affinity DataIC50: 564nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed