BDBM50333015 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone::CHEMBL1631540

SMILES Cc1ccc2c(cccc2n1)N1CCN(CCc2cccc(c2)N2CCNC2=O)CC1

InChI Key InChIKey=ANGUXJDGJCHGOG-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50333015   

TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human recombinant CYP219More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using atorvastatin as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandPNGBDBM50333015(1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]e...)
Affinity DataKi:  1.26E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed