BDBM50332797 CHEMBL1629794::N-[2-(10H-Phenothiazin-10-yl)ethyl]-4-methylpiperazin-1-amine dihydrochloride

SMILES CN1CCN(CC1)NCCN1c2ccccc2Sc2ccccc12

InChI Key InChIKey=MWUAENAQTGSUCO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332797   

TargetAcetylcholinesterase(Bovine)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50332797(N-[2-(10H-Phenothiazin-10-yl)ethyl]-4-methylpipera...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetCholinesterase(Horse)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50332797(N-[2-(10H-Phenothiazin-10-yl)ethyl]-4-methylpipera...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAlpha-synuclein(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50332797(N-[2-(10H-Phenothiazin-10-yl)ethyl]-4-methylpipera...)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAlpha-synuclein(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50332797(N-[2-(10H-Phenothiazin-10-yl)ethyl]-4-methylpipera...)
Affinity DataKi: >500nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed