BDBM50332612 1-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-piperidin-1-yl)-2-(methylsulfonyl)ethanone::CHEMBL1630799

SMILES CC1CCN(CC1N(C)c1ncnc2[nH]ccc12)C(=O)CS(C)(=O)=O

InChI Key InChIKey=BUNOUGVLAYVGAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332612   

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332612(1-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human JAK1 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332612(1-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 147nMAssay Description:Inhibition of GST-tagged human JAK3 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed