BDBM50332595 CHEMBL1630764::N-Cycloheptyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES CN(C1CCCCCC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=LMWSFHNYYHRQTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332595   

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332595(N-Cycloheptyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GST-tagged human JAK1 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332595(N-Cycloheptyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of GST-tagged human JAK3 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed