BDBM50332556 CHEMBL1630704::US8470841, 4::trans-N-(3-(5-(4-(benzyloxy)phenoxy)-1,3-dioxan-2-yl)propyl)acetamide

SMILES CC(=O)NCCC[C@H]1OC[C@@H](CO1)Oc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=CJOWXYBQBCABKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332556   

TargetAcetyl-CoA carboxylase 2 [151-2458](Human)
Sanofi

US Patent
LigandPNGBDBM50332556(US8470841, 4 | CHEMBL1630704 | trans-N-(3-(5-(4-(b...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 50 mM tris acetate (Merck, #1.08382.1000), pH 7.5, 250 μM acetyl coenzyme A (Sigma, #A2181),16 mM NaHCO3 (Merck, #1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332556(US8470841, 4 | CHEMBL1630704 | trans-N-(3-(5-(4-(b...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332556(US8470841, 4 | CHEMBL1630704 | trans-N-(3-(5-(4-(b...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332556(US8470841, 4 | CHEMBL1630704 | trans-N-(3-(5-(4-(b...)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed