BDBM50332552 CHEMBL1630708::N-(4-(4-(5-(cyclopentyloxy)pyridin-2-yloxy)phenyl)butan-2-yl)acetamide::US8470841, 2

SMILES CC(CCc1ccc(Oc2ccc(OC3CCCC3)cn2)cc1)NC(C)=O

InChI Key InChIKey=JOPQLBJOBLLJOI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332552   

TargetAcetyl-CoA carboxylase 2 [151-2458](Human)
Sanofi

US Patent
LigandPNGBDBM50332552(US8470841, 2 | CHEMBL1630708 | N-(4-(4-(5-(cyclope...)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 50 mM tris acetate (Merck, #1.08382.1000), pH 7.5, 250 μM acetyl coenzyme A (Sigma, #A2181),16 mM NaHCO3 (Merck, #1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332552(US8470841, 2 | CHEMBL1630708 | N-(4-(4-(5-(cyclope...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332552(US8470841, 2 | CHEMBL1630708 | N-(4-(4-(5-(cyclope...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332552(US8470841, 2 | CHEMBL1630708 | N-(4-(4-(5-(cyclope...)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed