BDBM50332297 CHEMBL1287812::ethyl 3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)benzoate

SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1

InChI Key InChIKey=JPUYPWPBMDSISN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332297   

TargetTyrosine-protein kinase JAK1(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50332297(ethyl 3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of human recombinant JAK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50332297(ethyl 3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant JAK2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50332297(ethyl 3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant JAK3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50332297(ethyl 3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human recombinant TYK2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed