BDBM50332088 CHEMBL1288128::N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoquinolin-5-yl)acetamide

SMILES O=C(Cc1cccc2cnccc12)Nc1scnc1-c1nnc[nH]1

InChI Key InChIKey=CCEORUFGHAKXQE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332088   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332088(N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoqu...)
Affinity DataIC50: 710nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332088(N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoqu...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332088(N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoqu...)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332088(N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoqu...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant Erk2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332088(N-(4-(1H-1,2,4-triazol-3-yl)thiazol-5-yl)-2-(isoqu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed