BDBM50332064 CHEMBL1287859::methyl 4-(2-(naphthalen-1-yl)acetamido)thiophene-3-carboxylate

SMILES COC(=O)c1cscc1NC(=O)Cc1cccc2ccccc12

InChI Key InChIKey=TYOBDVZTZRJMQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332064   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332064(methyl 4-(2-(naphthalen-1-yl)acetamido)thiophene-3...)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332064(methyl 4-(2-(naphthalen-1-yl)acetamido)thiophene-3...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332064(methyl 4-(2-(naphthalen-1-yl)acetamido)thiophene-3...)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed