BDBM50331943 5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-one::CHEMBL1290004

SMILES O=C(N1CCCCC1)c1ccccc1N1Cn2c(ccc2-c2ccccc2)C1=O

InChI Key InChIKey=KHHBKFYFMHFBOI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50331943   

TargetNeuropeptide S receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed