BDBM50331887 (2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::(S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::CHEMBL1230348

SMILES c1c(cc(c2c1C=C([C@H](O2)C(F)(F)F)C(=O)O)Cl)Cl

InChI Key InChIKey=ZFKBWSREWJOSSJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331887   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)