BDBM50331886 6-chloro-8-((4-sulfamoylphenyl)ethynyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::CHEMBL1290434

SMILES NS(=O)(=O)c1ccc(cc1)C#Cc1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O

InChI Key InChIKey=WNFIMLNJZQTRHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331886   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331886(6-chloro-8-((4-sulfamoylphenyl)ethynyl)-2-(trifluo...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331886(6-chloro-8-((4-sulfamoylphenyl)ethynyl)-2-(trifluo...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed