BDBM50331827 6-(cyclobutylamino)-9-fluorobenzo[c][1,6]naphthyridin-1(2H)-one::CHEMBL1290769

SMILES Fc1ccc2c(NC3CCC3)nc3cc[nH]c(=O)c3c2c1

InChI Key InChIKey=UQGCDSQHWUMCPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331827   

TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50331827(6-(cyclobutylamino)-9-fluorobenzo[c][1,6]naphthyri...)
Affinity DataIC50: 75nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed