BDBM50331813 2-(1-(2,4-dichloro-5-fluorophenyl)ethylamino)-3-(4-fluorophenyl)-1,6-naphthyridin-5(6H)-one::CHEMBL1290090

SMILES CC(Nc1nc2cc[nH]c(=O)c2cc1-c1ccc(F)cc1)c1cc(F)c(Cl)cc1Cl

InChI Key InChIKey=WBSBRCJNWZWMFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331813   

TargetTyrosine-protein kinase JAK2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50331813(2-(1-(2,4-dichloro-5-fluorophenyl)ethylamino)-3-(4...)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed