BDBM50331796 1,1,1-trifluoro-2-(1-((2-(1-hydroxyethyl)-3-phenylbenzo[b]thiophen-6-yl)methyl)-1H-1,2,3-triazol-4-yl)butan-2-ol::CHEMBL1289214

SMILES CCC(O)(c1cn(Cc2ccc3c(c(sc3c2)C(C)O)-c2ccccc2)nn1)C(F)(F)F

InChI Key InChIKey=OGKPZQUWFNSSNB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331796   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331796(1,1,1-trifluoro-2-(1-((2-(1-hydroxyethyl)-3-phenyl...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331796(1,1,1-trifluoro-2-(1-((2-(1-hydroxyethyl)-3-phenyl...)
Affinity DataIC50: 161nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331796(1,1,1-trifluoro-2-(1-((2-(1-hydroxyethyl)-3-phenyl...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of labeled MK-499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed