BDBM50331708 6,7-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-carbazol-1-ol::CHEMBL1288321

SMILES OC1(CCCc2c1[nH]c1cc(Cl)c(Cl)cc21)C(F)(F)F

InChI Key InChIKey=OZXBEIHRSWLQHT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331708   

TargetAndrogen receptor(Human)
Radius Health

US Patent
LigandPNGBDBM50331708(6,7-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...)
Affinity DataIC50: 1.56E+3nMT: 2°CAssay Description:In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Radius Health

US Patent
LigandPNGBDBM50331708(6,7-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...)
Affinity DataIC50: 27nMAssay Description:Binding affinity to androgen receptor by fluorescence binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Radius Health

US Patent
LigandPNGBDBM50331708(6,7-dichloro-1-(trifluoromethyl)-2,3,4,9-tetrahydr...)
Affinity DataEC50:  27nMAssay Description:Modulation of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed