BDBM50331648 CHEMBL1288914::methyl 4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-chloro-4-fluorobenzoyl)-4-(3-fluorophenyl)piperidin-4-yl)ethyl)piperidin-4-yl)ureido)methyl)benzoate

SMILES COC(=O)c1ccc(CNC(=O)N(CC=C)C2CCN(CCC3(CCN(CC3)C(=O)c3cc(c(F)cc3Cl)S(=O)(=O)NC(C)(C)C)c3cccc(F)c3)CC2)cc1

InChI Key InChIKey=DGJOXPXKQXPVLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331648   

TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331648(methyl 4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulf...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331648(methyl 4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulf...)
Affinity DataIC50: 146nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed