BDBM50331592 3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyrimidin-4-yl)phenol::CHEMBL1290744

SMILES COc1ccc(Nc2cc(nc(n2)N2CCOCC2)-c2cccc(O)c2)cn1

InChI Key InChIKey=YMQHMPUWBKBXEA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331592   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)
Affinity DataIC50: 240nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed