BDBM50331513 6.5.8. 2-Naphthylmethyl-4-(3,4-dichlorophenyl)-1-methylpiperidine-4-carboxylate hydrochloride::CHEMBL1290174

SMILES CN1CCC(CC1)(C(=O)OCc1ccc2ccccc2c1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=UHHMZXPWZFKHSN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331513   

TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50331513(6.5.8. 2-Naphthylmethyl-4-(3,4-dichlorophenyl)-1-m...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50331513(6.5.8. 2-Naphthylmethyl-4-(3,4-dichlorophenyl)-1-m...)
Affinity DataKi:  2.55E+3nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50331513(6.5.8. 2-Naphthylmethyl-4-(3,4-dichlorophenyl)-1-m...)
Affinity DataKi:  4.91E+3nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed