BDBM50331319 (+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)-1-(4-fluorophenyl)butan-1-one::CHEMBL1289955

SMILES OC1CN(CCCC(=O)c2ccc(F)cc2)CCc2cc(O)ccc12

InChI Key InChIKey=LEBXQVNFNPRKSC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331319   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331319((+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-ben...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331319((+/-)-4-(1,7-Dihydroxy-2,3,4,5-tetrahydro-1H-3-ben...)
Affinity DataKi:  1.05E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed