BDBM50331307 CHEMBL1289058::trans-7-(Benzyloxy)-3-(4-phenylcyclohexyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

SMILES OC1CN(CCc2cc(OCc3ccccc3)ccc12)[C@H]1CC[C@@H](CC1)c1ccccc1

InChI Key InChIKey=PTTOPMPFOOSPSM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331307   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331307(trans-7-(Benzyloxy)-3-(4-phenylcyclohexyl)-2,3,4,5...)
Affinity DataKi:  386nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331307(trans-7-(Benzyloxy)-3-(4-phenylcyclohexyl)-2,3,4,5...)
Affinity DataKi:  388nMAssay Description:Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed