BDBM50331298 (+/-)-7-(Benzyloxy)-3-{3-[2-(4-tert-butylphenyl)-5,5-dimethyl-1,3-dioxan-2-yl]propyl}-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol::CHEMBL1290270

SMILES CC(C)(C)c1ccc(cc1)C1(CCCN2CCc3cc(OCc4ccccc4)ccc3C(O)C2)OCC(C)(C)CO1

InChI Key InChIKey=ZLRSPZURKJYEMQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331298   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331298((+/-)-7-(Benzyloxy)-3-{3-[2-(4-tert-butylphenyl)-5...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50331298((+/-)-7-(Benzyloxy)-3-{3-[2-(4-tert-butylphenyl)-5...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed