BDBM50331234 (S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one::CHEMBL1289515

SMILES O[C@H]1CCN(CCn2ncc3cc(ccc23)-n2ccc(OCc3ccccc3)cc2=O)C1

InChI Key InChIKey=DZPCZIBGZIYEKK-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50331234   

TargetCytochrome P450 2D6(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by mini-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331234((S)-4-(benzyloxy)-1-(1-(2-(3-hydroxypyrrolidin-1-y...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed