BDBM50330814 CHEMBL1275791::[(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-dimethylamine

SMILES CN(C)[C@H]1CC[C@H](C1)c1c[nH]c2ccc(F)cc12

InChI Key InChIKey=LRSVJJWABVMKRA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50330814   

Target5-hydroxytryptamine receptor 4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:Binding affinity to dopamine D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 1.70nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 0.630nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 500nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 2.80E+4nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50330814([(1R,3S)-3-(5-Fluoro-1H-indol-3-yl)-cyclopentyl]-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed