BDBM50330789 CHEMBL1277501::N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-propane-1,3-diamine

SMILES CNCCCN(c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=XNCBCWQLSZMOOC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330789   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed