BDBM50330534 3-(2-fluorophenylsulfonyl)-5-(4-methylpiperazin-1-yl)-1H-indazole::CHEMBL1277998

SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1F

InChI Key InChIKey=PGWCUSVMUGTCQQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330534   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330534(3-(2-fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330534(3-(2-fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed