BDBM50330527 1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1278092

SMILES Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=RSVABANYROVMSW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330527   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330527(1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330527(1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed