BDBM50330526 1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole::CHEMBL1278001

SMILES O=S(=O)(c1nn(Cc2ccccc2)c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12

InChI Key InChIKey=CPKUIKQUAANRIQ-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50330526   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  605nMAssay Description:Displacement of [3H]LSD from human cloned dopamine D2 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2C receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1B receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT1D receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]LSD from human cloned alpha2A adrenergic receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed