BDBM50330459 3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3H-quinazolin-4-one::CHEMBL1277651

SMILES Nn1c(CCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2ccccc2c1=O

InChI Key InChIKey=GTIKAAJNYPWELX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330459   

Target5-hydroxytryptamine receptor 1A(Human)
Aska Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50330459(3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]...)
Affinity DataEC50:  30.7nMAssay Description:Agonist activity at human cloned 5HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 30 mins by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Aska Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50330459(3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]...)
Affinity DataIC50: 45.7nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed