BDBM50330437 1,6-di-O-phosphono-D-fructose::2,3,4-trihydroxy-5-oxohexane-1,6-diyl bis(dihydrogen phosphate)::CHEMBL1235112

SMILES OC(COP(O)(O)=O)[C@@H](O)C(=O)[C@H](O)COP(O)(O)=O

InChI Key InChIKey=PMWDZCANQJYEEV-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50330437   

TargetFructose-bisphosphate aldolase A(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of rabbit muscle FBA assessed as inhibition of FBP cleavage by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase, glycosomal(Trypanosoma brucei brucei)
TBA

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase A(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of rabbit muscle zinc dependent class 1 Fba expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of Helicobacter pylori recombinant zinc dependent class 2 Fba expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis zinc dependent class 2 FbaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase(Yersinia pestis)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of Yersinia pestis zinc dependent class 2 Fba expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetFructose-bisphosphate aldolase(Yeast)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50330437(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of Candida albicans zinc dependent class 2 FbaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed