BDBM50329966 2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-benzo[d]imidazole::CHEMBL1272304

SMILES CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccccc1F

InChI Key InChIKey=OBNJEGKQRUDUQM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50329966   

TargetStearoyl-CoA desaturase 5(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human SCD5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat Delta(5) fatty acid desaturase by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of Delta(5) fatty acid desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of Delta(5) fatty acid desaturase in freshly isolated rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 65nMAssay Description:Inhibition of rat SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed