BDBM50329901 2-(5-aminopyridin-2-yl)-5-chloro-6-methylpyrimidin-4-ol::CHEMBL1269394

SMILES Cc1nc([nH]c(=O)c1Cl)-c1ccc(N)cn1

InChI Key InChIKey=KOWIVPQBUIHTSO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329901   

TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329901(2-(5-aminopyridin-2-yl)-5-chloro-6-methylpyrimidin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed