BDBM50329898 2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimidin-2-yl)pyridin-3-yl)acetamide::CHEMBL1272037

SMILES FC(F)(F)c1cc(Cl)nc(n1)-c1ccc(NC(=O)CCl)cn1

InChI Key InChIKey=RGHCKPXBEZDOJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329898   

TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329898(2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329898(2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimid...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed