BDBM50329893 2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-4-ol::CHEMBL1269397

SMILES Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1

InChI Key InChIKey=WEXIMUHIBVNFJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329893   

TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329893(2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329893(2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed