BDBM50329889 CHEMBL1271868::N-(6-(5-benzyl-4-hydroxy-6-methylpyrimidin-2-yl)pyridin-3-yl)-2-chloroacetamide

SMILES Cc1nc([nH]c(=O)c1Cc1ccccc1)-c1ccc(NC(=O)CCl)cn1

InChI Key InChIKey=IDOAXXIIOYRVNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329889   

TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329889(N-(6-(5-benzyl-4-hydroxy-6-methylpyrimidin-2-yl)py...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329889(N-(6-(5-benzyl-4-hydroxy-6-methylpyrimidin-2-yl)py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed